Non-invasive prenatal test.
We analyze all the 24 chromosomes for the peace of mind of future mothers

We analyse all of the foetal chromosomes

Genetic syndromes detected* (Neo24+)

Neo24 reduces the number of unnecessary invasive prenatal tests

The Neo24 test successfully gives results in more samples than other tests

What is Neo24?

Neo24 is a non-invasive prenatal test, performed with maternal blood, completely safe for the mother and her unborn child. We analyze the 24 chromosomes for the peace of mind of future mothers. 

Enables established pregnancies (from 10 weeks of gestation) to be assessed for certain chromosome abnormalities that can lead to late miscarriages or the birth of a child with serious congenital abnormalities. Neo24 offers a high detection rate for the specific chromosome abnormalities tested and a low false-positive rate. Importantly, the non-invasive nature of the test means that it does not increase the risk of miscarriage unlike traditional invasive prenatal tests.

What are the benefits of Neo24?

Unlike more invasive prenatal testing methods, such as chorionic villi sampling (CVS) or amniocentesis, which sample cells from the placenta or fetus, Neo24 is based on a blood sample taken from the mother. It therefore poses no risk to the fetus and does not increase the chance of a pregnancy loss. This compares to increased risks of miscarriage following CVS and amniocentesis, usually estimated at 0.5%-1%. Medical societies agree that all pregnant women should be offered prenatal screening for fetal abnormalities. Neo24 represents a major advancement in prenatal screening methodologies.
From 10 weeks of gestation
Personalized genetic counseling pre and post test at the request of the doctor.
Reduces unnecessary amniocentesis by approximately 90%.
Results in 5-7 days




From week 10 or beyond


Blood sample taken


Sample sent


DNA Test


5-7 days

Order your Neo 24 Kit now and receive it in less than two days


Detects abnormalities in all 24 chromosomes

Valid for pregnancies occurring after natural conception, as well as those achieved using IVF technology, including pregnancies from egg or sperm donation. Neo24 does not require additional DNA samples from the two parents and is still applicable in cases of consanguinity. Neo24 is also validated for use in twin pregnancies. However, sex chromosome abnormalities cannot be detected when more than one foetus is present.

Who should use Neo24?

While Neo24 will provide potentially valuable information for any pregnancy, women with the following risk factors should give Neo24 particular consideration:

Testing can take place even in the absence of these risk factors.

Quien test prenatal neo24

How is Neo24 carried out in Juno Genetics?

Juno Genetics offers a cutting-edge non-invasive prenatal test solution, which examines all 24 types of chromosome. In contrast many other NIPT tests only examine a small number of chromosomes (typically chromosomes 13, 18, 21 and sometimes the sex chromosomes, X and Y). Juno’s Neo24 method is extremely sensitive, delivering one of the highest accuracy rates with the lowest incidence of samples that fail to give a result. The technique used is based upon next-generation sequencing (NGS) technology. A blood sample is taken from the pregnant mother from 10 weeks of gestation. Plasma is isolated from the sample, which contains millions of DNA fragments from the mother and also from the fetus mixed together. These cell-free DNA (cfDNA) fragments are sequenced and a sophisticated analysis is undertaken in order to determine the number of copies of each chromosome.

The analysis reveals the proportion of the cfDNA fragments that come from the fetus and which chromosome each piece of cfDNA originally came from. If an excessive proportion of the cfDNA fragments come from a particular chromosome, this is indicative of the presence of an extra copy of that chromosome. This sort of abnormality, known as ‘trisomy’ is the most common form of aneuploidy seen during pregnancy and explains most miscarriages as well as conditions that can affect liveborn children, such as Down syndrome. Rarer forms of abnormality, such as loss of a chromosomes (monosomy), or abnormalities involving loss or duplication of large pieces of chromosome (>7Mb) can also potentially be detected using the Juno Neo24 test.

What are the limitations of Neo24?

Neo24 is a screening test that only look for specific chromosomal abnormalities. This means that other chromosomal abnormalities may be present and could affect the pregnancy. A “No Aneuploidy Detected” result does not guarantee a healthy pregnancy or baby, and does not eliminate the possibility that a fetus may have birth defects, genetic disorders, or other conditions, such as open neural tube defects or autism. There is a small possibility that the test results might only reflect the chromosomes of the placenta and not those of the fetus (this is known as confined placental mosaicism, CPM).

Additionally, the results of the test may be confused if some of the cells of the mother have an abnormal number of chromosomes. In the case of a twin pregnancy, the presence or absence of Y chromosome material can be reported, but it will not be clear whether both twins are male or just one of them. Furthermore, abnormalities affecting the sex chromosomes cannot be evaluated in twin pregnancies.
Because of the limitations outlined above, no irreversible clinical decisions should be made based on Neo24 results alone. If a definitive diagnosis is desired, chorionic villus sampling or amniocentesis would be necessary.

Neo24 test results are usually available within 5 days of Juno receiving the sample of maternal blood (although up to 10 days may be required)

They are tests that are performed before the baby is born and in which the sample to be studied is not obtained directly from the foetus, but from its DNA that is found freely circulating in the mother’s blood, which is why it is non-invasive.

With this test we can detect the presence of certain abnormalities in any of the foetus’ 24 chromosomes. It detects anomalies like trisomies 21, 18 and 13 (Down, Edwards and Patau Syndromes) and the anomalies generated by the sex chromosomes (X and Y).


Clinical documentation

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