In some cases, embryos contain a mixture of cells, some having the correct number of chromosomes and others having an abnormal chromosome number. Such embryos are said to be ‘mosaic’. Some studies have suggested that mosaic embryos are less likely to produce a healthy pregnancy than those that have only normal cells in their biopsy specimen. However, other studies have provided contradictory information. The PGT[A]seq method used by Juno Genetics reveals when an embryo sample contains a mixture normal and abnormal cells. Any mosaic embryos detected during PGT-A will be indicated in the report issued by Juno. The choice of whether or not mosaic embryos are transferred to the uterus depends on the policy of the IVF clinic as well as national guidelines. It is recommended that transfer is considered only after consultation with a qualified healthcare professional.
